Trial Profile

Phase I/Ib Clinical Trial of Autologous CD22 Chimeric Antigen Receptor (CAR) T Cells Following Commercial CD19 CAR T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 13 Feb 2026

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At a glance

Drugs CAR-T cell therapies (Primary) ; Tisagenlecleucel (Primary)
Indications B-cell leukaemia; Precursor B-cell lymphoblastic leukaemia-lymphoma
Focus Adverse reactions; Therapeutic Use

10 Feb 2026 Planned End Date changed from 1 Nov 2025 to 1 Jul 2026.
10 Feb 2026 Planned primary completion date changed from 1 Nov 2025 to 1 Jul 2026.
06 Jun 2025 Planned End Date changed from 1 Jun 2025 to 1 Nov 2025.

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