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An EBV mRNA Vaccine (WGc-043 Injection) in Patients With EB Virus-positive Relapsed or Refractory Lymphoma: A Phase I Clinical Trial Assessing the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Preliminary Anti-tumor Activity

Trial Profile

An EBV mRNA Vaccine (WGc-043 Injection) in Patients With EB Virus-positive Relapsed or Refractory Lymphoma: A Phase I Clinical Trial Assessing the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Preliminary Anti-tumor Activity

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 07 Apr 2025

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At a glance

  • Drugs WGc 043 (Primary)
  • Indications Diffuse large B cell lymphoma; Lymphoma; Peripheral T-cell lymphoma; T-cell lymphoma
  • Focus Therapeutic Use

Most Recent Events

  • 28 Mar 2025 Planned initiation date changed from 10 Feb 2025 to 1 Apr 2025.
  • 16 Sep 2024 According to a WestGene Biopharma media release, clinical data from this study presented as mini-oral presentation at the European Society for Medical Oncology (ESMO) Congress 2024.
  • 07 Aug 2024 According to a WestGene Biopharma media release, the company announce that WGc-043, has received dual IND approvals from China's National Medical Products Administration (NMPA) and the US FDA, allowing the initiation of this Phase I clinical trials.

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