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A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations

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Trial Profile

A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 22 Mar 2026

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At a glance

  • Drugs Adagrasib (Primary) ; Cemiplimab (Primary) ; Cetuximab (Primary)
  • Indications Colorectal cancer
  • Focus Adverse reactions

Most Recent Events

  • 06 Mar 2026 Planned End Date changed from 1 Mar 2028 to 1 Mar 2029.
  • 06 Mar 2026 Planned primary completion date changed from 1 Mar 2026 to 1 Mar 2029.
  • 19 Sep 2024 Status changed from suspended to recruiting.

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