To Assess Mechanisms Linking Immune Checkpoint Inhibitor Pharmacokinetics and Outcomes in Cancer Patients
Latest Information Update: 21 May 2024
At a glance
- Drugs Carboplatin (Primary) ; Ipilimumab (Primary) ; Nivolumab (Primary) ; Paclitaxel (Primary) ; Pembrolizumab (Primary) ; Pemetrexed (Primary)
- Indications Cancer; Non-small cell lung cancer; Renal cell carcinoma
- Focus Pharmacokinetics
- 21 May 2024 New trial record
- 29 Mar 2024 Results assessing minimal sampling scheme using pre-dose and within 30 minutes post-dose across 4 consecutive cycles of treatment to estimate baseline and time-varying clearance and to assess underlying mechanisms linking ICI CL0 and Fc Receptors in cancer patients presented at the 125th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics