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A Phase 1/2, Randomized, Double-blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Safety, Tolerability, Efficacy, Pharmacodynamics, and Pharmacokinetics of Zilebesiran in Japanese Patients With Mild to Moderate Hypertension

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Trial Profile

A Phase 1/2, Randomized, Double-blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Safety, Tolerability, Efficacy, Pharmacodynamics, and Pharmacokinetics of Zilebesiran in Japanese Patients With Mild to Moderate Hypertension

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 02 May 2026

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At a glance

  • Drugs Zilebesiran (Primary)
  • Indications Hypertension
  • Focus Adverse reactions
  • Sponsors Alnylam Pharmaceuticals

Most Recent Events

  • 29 Aug 2025 Status changed from active, no longer recruiting to completed.
  • 29 Aug 2024 Status changed from recruiting to active, no longer recruiting.
  • 28 Jun 2024 Status changed from not yet recruiting to recruiting.

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