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A Phase 1, Open-Label, Multicenter, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics/Pharmacodynamics, and Preliminary Efficacy of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors

Trial Profile

A Phase 1, Open-Label, Multicenter, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics/Pharmacodynamics, and Preliminary Efficacy of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 09 May 2025

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At a glance

  • Drugs ISM 3412 (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors InSilico Medicine

Most Recent Events

  • 06 Jan 2025 Status changed from not yet recruiting to recruiting.
  • 24 May 2024 New trial record
  • 25 Apr 2024 According to an InSilico Medicine media release, the company has received approval from the U.S. Food and Drug Administration (FDA) for its Investigational New Drug (IND) application for ISM3412.

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