An Open Label, Multicenter, Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Profile of the PARP1 Inhibitor M9466 Alone or in Combination in Participants With Advanced Solid Tumors
Latest Information Update: 15 May 2025
At a glance
- Drugs HRS-1167 (Primary) ; Tuvusertib (Primary)
- Indications Solid tumours
- Focus Adverse reactions; Pharmacokinetics
- Acronyms DDRiver 501
Most Recent Events
- 19 Dec 2024 Planned number of patients changed from 90 to 96.
- 27 Nov 2024 Planned number of patients changed from 70 to 90.
- 15 Aug 2024 Planned initiation date changed from 2 Aug 2024 to 7 Aug 2024.