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A Phase 1, Randomized, Double-blind, Placebo-controlled, Parallel Study Evaluating the Effects of Single Doses of NaV1.8 Inhibitors on C-Nociceptor Action Potentials in Healthy Adults

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Trial Profile

A Phase 1, Randomized, Double-blind, Placebo-controlled, Parallel Study Evaluating the Effects of Single Doses of NaV1.8 Inhibitors on C-Nociceptor Action Potentials in Healthy Adults

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 23 Apr 2025

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At a glance

  • Drugs Suzetrigine (Primary) ; VX 150 (Primary)
  • Indications Pain
  • Focus Pharmacodynamics
  • Sponsors Vertex Pharmaceuticals

Most Recent Events

  • 20 Apr 2025 Status changed from recruiting to completed.
  • 16 Jan 2025 Planned number of patients changed from 40 to 92.
  • 16 Jan 2025 Planned End Date changed from 1 Sep 2025 to 18 Apr 2025.

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