Trial Profile

A Phase 1 Study Investigating the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of BGB-C354, an Antibody-Drug Conjugate Targeting B7H3, Alone and in Combination With Anti-PD-1 Monoclonal Antibody Tislelizumab in Patients With Advanced Solid Tumors

Status: Discontinued

Phase of Trial: Phase I

Latest Information Update: 24 Mar 2026

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At a glance

17 Mar 2026 Status changed from active, no longer recruiting to discontinued as the BGB-C354 development has been discontinued by the company, according to a BeOne Medicines 10K filing.
17 Feb 2026 Status changed from recruiting to active, no longer recruiting.
28 Jul 2025 Planned number of patients changed from 62 to 120.

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