Trial Profile

A Phase 1 Study Investigating the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of BGB-C354, an Antibody-Drug Conjugate Targeting B7H3, Alone and in Combination With Anti-PD-1 Monoclonal Antibody Tislelizumab in Patients With Advanced Solid Tumors

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 24 Sep 2025

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At a glance

28 Jul 2025 Planned number of patients changed from 62 to 120.
28 Jul 2025 Planned End Date changed from 30 Nov 2026 to 31 Jan 2027.
28 Jul 2025 Planned primary completion date changed from 30 Nov 2026 to 1 Dec 2026.

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