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A Phase 1, Randomized, 2-part, 7-way Cross-over (Part 1) and 7-way Cross-over (Part 2), Active Device Blinded, Single Dose Study in Mild Asthmatics Aged 18-65 to Assess the Relative Potency of Salbutamol Administered Via Metered Dose Inhalers Containing Propellants HFA-152a (Test) and HFA-134a (Reference) Via Methacholine Bronchoprovocation and Systemic Pharmacodynamic Effects

Trial Profile

A Phase 1, Randomized, 2-part, 7-way Cross-over (Part 1) and 7-way Cross-over (Part 2), Active Device Blinded, Single Dose Study in Mild Asthmatics Aged 18-65 to Assess the Relative Potency of Salbutamol Administered Via Metered Dose Inhalers Containing Propellants HFA-152a (Test) and HFA-134a (Reference) Via Methacholine Bronchoprovocation and Systemic Pharmacodynamic Effects

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 21 May 2025

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At a glance

  • Drugs Salbutamol (Primary)
  • Indications Asthma
  • Focus Therapeutic Use
  • Sponsors GSK

Most Recent Events

  • 13 May 2025 Planned End Date changed from 18 Mar 2025 to 14 Aug 2026.
  • 13 May 2025 Planned primary completion date changed from 13 Mar 2025 to 14 Aug 2026.
  • 05 Nov 2024 Planned End Date changed from 15 Oct 2024 to 18 Mar 2025.

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