Phase 1b/2 Study of Decitabine and Venetoclax in Combination With the Targeted Mutant IDH1 Inhibitor Olutasidenib
Latest Information Update: 14 Feb 2025
At a glance
- Drugs Decitabine (Primary) ; Olutasidenib (Primary) ; Venetoclax (Primary)
- Indications Acute myeloid leukaemia; Myelodysplastic syndromes
- Focus Adverse reactions
Most Recent Events
- 10 Dec 2024 Trial design presented at the 66th American Society of Hematology Annual Meeting and Exposition.
- 05 Sep 2024 According to a Rigel Pharmaceuticals media release, company announced the first patient has been enrolled in a Phase 1b/2 triplet therapy trial of decitabine and venetoclax in combination with REZLIDHIA (olutasidenib) in patients with mutated isocitrate dehydrogenase-1 (mIDH1) acute myeloid leukemia (AML).
- 04 Sep 2024 Status changed from not yet recruiting to recruiting.