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A Phase II, Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumor Activity of Volrustomig Priming Regimens in Combination With Other Anticancer Agents in Participants With Solid Tumors (eVOLVE-01)

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Trial Profile

A Phase II, Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumor Activity of Volrustomig Priming Regimens in Combination With Other Anticancer Agents in Participants With Solid Tumors (eVOLVE-01)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 16 Feb 2025

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At a glance

  • Drugs Carboplatin (Primary) ; Pemetrexed (Primary) ; Volrustomig (Primary)
  • Indications Non-small cell lung cancer; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms eVOLVE-01
  • Sponsors AstraZeneca
  • Most Recent Events

    • 08 Oct 2024 Planned End Date changed from 19 Oct 2026 to 8 Dec 2026.
    • 08 Oct 2024 Planned primary completion date changed from 16 Sep 2025 to 6 Nov 2025.
    • 08 Oct 2024 Status changed from not yet recruiting to recruiting.

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