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A Phase 1b Study of the Multi-Kinase Inhibitor Regorafenib in Combination With the BCL-2 Inhibitor Venetoclax Plus Azacitidine in Patients With Relapsed/Refractory Acute Myeloid Leukemia

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Trial Profile

A Phase 1b Study of the Multi-Kinase Inhibitor Regorafenib in Combination With the BCL-2 Inhibitor Venetoclax Plus Azacitidine in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Status: Suspended
Phase of Trial: Phase I

Latest Information Update: 30 May 2025

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At a glance

  • Drugs Azacitidine (Primary) ; Regorafenib (Primary) ; Venetoclax (Primary)
  • Indications Acute myeloid leukaemia; Myelodysplastic syndromes
  • Focus Adverse reactions

Most Recent Events

  • 26 May 2025 Status changed to suspended.
  • 26 May 2025 Planned End Date changed from 17 Feb 2027 to 6 Sep 2030.
  • 26 May 2025 Planned primary completion date changed from 17 Feb 2027 to 6 Sep 2030.

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