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Study of vorinostat (RVL-001) in patients with Pitt Hopkins Syndrome (PTHS)

Trial Profile

Study of vorinostat (RVL-001) in patients with Pitt Hopkins Syndrome (PTHS)

Status: Planning
Phase of Trial: Phase I

Latest Information Update: 30 Oct 2024

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At a glance

  • Drugs Vorinostat (Primary)
  • Indications Pitt-Hopkins syndrome
  • Focus Adverse reactions; Proof of concept
  • Most Recent Events

    • 24 Oct 2024 According to an Unravel Biosciences media release, initiation of patient dosing for the RVL-001 trial in RTT and extension trial in PTHS are both anticipated in early 2025.
    • 14 Jun 2024 New trial record
    • 11 Jun 2024 According to an Unravel Biosciences media release, the company announced a collaboration to conduct a proof of concept clinical trial of vorinostat (RVL-001) in patients with Pitt Hopkins Syndrome (PTHS).Under the terms of the collaboration, the Foundation will fund the clinical trial conducted by Unravel at its study site in Colombia and Unravel will retain rights for further development and commercialization.

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