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A Single-Arm Registrational Phase III Study of Olverembatinib in the Treatment of Patients With SDH-Deficient Gastrointestinal Stromal Tumor (POLARIS-3)

Trial Profile

A Single-Arm Registrational Phase III Study of Olverembatinib in the Treatment of Patients With SDH-Deficient Gastrointestinal Stromal Tumor (POLARIS-3)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 31 Dec 2024

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At a glance

  • Drugs Olverembatinib (Primary)
  • Indications Gastrointestinal stromal tumours
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms POLARIS-3
  • Sponsors Ascentage Pharma

Most Recent Events

  • 27 Dec 2024 Status changed from not yet recruiting to recruiting.
  • 17 Oct 2024 Status changed from planning to not yet recruiting.
  • 08 Sep 2024 According to an Ascentage Pharma media release, the company will present the latest clinical data of olverembatinib (HQP1351), in patients with succinate dehydrogenase- (SDH-) deficient gastrointestinal stromal tumor (GIST), in a Mini Oral at the 2024 European Society of Medical Oncology (ESMO) Congress held from September 13 to 17 in Barcelona, Spain. The presentation will be done on September 13, 2024, 16:30 -16:35 CEST, by Haibo Qiu, MD, PhD, Sun Yat-sen University Cancer Center (no. 1722MO).

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