Trial Profile

A Phase II Multicenter Open-label Trial of Tagraxofusp (Tag) in Combination With Venetoclax and Azacitidine (Ven/Aza) in Adults With Previously Untreated CD123+ Acute Myeloid Leukemia (AML) Who Are Ineligible for Intensive Chemotherapy

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 15 Jun 2025

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At a glance

Drugs Azacitidine (Primary) ; Azacitidine (Primary) ; Tagraxofusp (Primary) ; Venetoclax (Primary)
Indications Acute myeloid leukaemia
Focus Therapeutic Use
Acronyms TRILLIUM
Sponsors Stemline Therapeutics

30 Apr 2025 Trial design presented at the 116th Annual Meeting of the American Association for Cancer Research
24 Dec 2024 Planned initiation date changed from 30 Nov 2024 to 1 Dec 2024.
24 Dec 2024 Status changed from not yet recruiting to recruiting.

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