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A Phase 3 Randomized, Active-controlled, Open-label, Multicenter Study to Compare the Efficacy and Safety of MK-2870 Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (TroFuse-020/GOG-3101/ENGOT-cx20)

Trial Profile

A Phase 3 Randomized, Active-controlled, Open-label, Multicenter Study to Compare the Efficacy and Safety of MK-2870 Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (TroFuse-020/GOG-3101/ENGOT-cx20)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 15 Jun 2025

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At a glance

  • Drugs Sacituzumab Tirumotecan (Primary) ; Gemcitabine; Irinotecan; Pemetrexed; Tisotumab-vedotin; Topotecan; Vinorelbine
  • Indications Adenocarcinoma; Adenosquamous carcinoma; Cervical cancer; Squamous cell cancer
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Sponsors Merck Sharp & Dohme

Most Recent Events

  • 30 Jul 2024 Status changed from not yet recruiting to recruiting.
  • 17 Jun 2024 New trial record

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