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Phase 1, Open-Label, Single Center Study of KYV-101, an Autologous Fully-Human Anti-CD19 Chimeric Antigen Receptor T Cell (CD19 CAR T) Therapy, in Participants with Treatment Refractory Progressive Multiple Sclerosis

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Trial Profile

Phase 1, Open-Label, Single Center Study of KYV-101, an Autologous Fully-Human Anti-CD19 Chimeric Antigen Receptor T Cell (CD19 CAR T) Therapy, in Participants with Treatment Refractory Progressive Multiple Sclerosis

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 22 Jan 2025

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At a glance

  • Drugs KYV-101 (Primary) ; Cyclophosphamide; Fludarabine
  • Indications Multiple sclerosis
  • Focus Adverse reactions; Pharmacokinetics

    • Most Recent Events

    • 20 Jan 2025 Status changed from recruiting to active, no longer recruiting.
    • 10 Dec 2024 Trial design presented at the 66th American Society of Hematology Annual Meeting and Exposition.
    • 18 Jun 2024 New trial record

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