Trial Profile

Phase 2 Study of Combination Pirtobrutinib (LOXO-305) and Venetoclax in CLL Patients With Resistance to Covalent BTKi

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 24 Feb 2026

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At a glance

Drugs Pirtobrutinib (Primary) ; Venetoclax (Primary)
Indications Chronic lymphocytic leukaemia
Focus Therapeutic Use

Most Recent Events

19 Feb 2026 Planned End Date changed from 31 Dec 2025 to 31 Dec 2026.
19 Feb 2026 Planned primary completion date changed from 31 Dec 2025 to 31 Dec 2026.
26 Jul 2024 Status changed from not yet recruiting to recruiting.

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