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Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies

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Trial Profile

Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 20 Feb 2025

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At a glance

  • Drugs Azacitidine (Primary) ; Methotrexate (Primary) ; Nivolumab (Primary)
  • Indications CNS cancer; Ependymoma; Medulloblastoma
  • Focus Adverse reactions

Most Recent Events

  • 23 Jul 2024 Status changed from not yet recruiting to recruiting.
  • 24 Jun 2024 New trial record

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