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A Phase 1 Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of JCXH-211 (SElf-Replicating RNA IL-12) Intratumoral Injection in Patients With Recurrent or Progressive High-Grade Glioma

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Trial Profile

A Phase 1 Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of JCXH-211 (SElf-Replicating RNA IL-12) Intratumoral Injection in Patients With Recurrent or Progressive High-Grade Glioma

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 10 Mar 2025

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At a glance

  • Drugs JCXH-211 (Primary)
  • Indications Astrocytoma; Glioblastoma; Glioma
  • Focus Adverse reactions
  • Acronyms SERIL

    • Most Recent Events

    • 05 Mar 2025 Planned End Date changed from 1 Oct 2029 to 1 Oct 2030.
    • 05 Mar 2025 Planned primary completion date changed from 1 Oct 2026 to 1 Oct 2027.
    • 05 Mar 2025 Planned initiation date changed from 1 Feb 2025 to 1 May 2025.

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