Trial Profile

A Randomized, Double-Blind, Placebo-Controlled Multicenter Phase III Study to Assess Efficacy and Safety of Ropeginterferon Alfa-2b (P1101) in Adult Patients With Pre-fibrotic/Early Primary Myelofibrosis (PMF) or Overt PMF at Low or Intermediate-1 Risk According to DIPSS Plus (HOPE-PMF): The Core Study and Its Extension Study

Status: Active, no longer recruiting

Phase of Trial: Phase III

Latest Information Update: 21 Aug 2026

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At a glance

22 Jul 2026 Planned End Date changed from 30 Sep 2028 to 11 Jan 2029.
22 Jul 2026 Planned primary completion date changed from 30 Sep 2027 to 18 Nov 2027.
22 Jul 2026 Status changed from recruiting to active, no longer recruiting.

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