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A Phase 3 Randomized, Open-Label Study to Evaluate the Efficacy and Safety of Tobevibart + Elebsiran Combination Therapy in Participants With Chronic HDV Infection (ECLIPSE 1)

Trial Profile

A Phase 3 Randomized, Open-Label Study to Evaluate the Efficacy and Safety of Tobevibart + Elebsiran Combination Therapy in Participants With Chronic HDV Infection (ECLIPSE 1)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 16 Apr 2025

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At a glance

  • Drugs Elebsiran (Primary) ; Tobevibart (Primary)
  • Indications Hepatitis D
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms ECLIPSE 1
  • Sponsors Vir Biotechnology

Most Recent Events

  • 13 Mar 2025 According to a Vir Biotechnology media release, this study is a part of the company's registrational program named ECLIPSE, which is comprised of 2 Phase 3 studies (ECLIPSE 1 and ECLIPSE 2) and one phase 2b study (ECLIPSE 3). ECLIPSE program is designed to enable regulatory submissions to multiple regulatory agencies and to support reimbursement and access.
  • 13 Mar 2025 According to a Vir Biotechnology media release, first patient has been enrolled in this study.
  • 13 Mar 2025 According to a Vir Biotechnology media release, status changed from planning to recruiting.

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