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A Phase I Study Investigating the Combination of Cladribine, Low Dose Cytarabine and Sorafenib Alternating With Decitabine in Pediatric Relapsed and Refractory Acute Leukemias

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Trial Profile

A Phase I Study Investigating the Combination of Cladribine, Low Dose Cytarabine and Sorafenib Alternating With Decitabine in Pediatric Relapsed and Refractory Acute Leukemias

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 07 Feb 2025

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At a glance

  • Drugs Cladribine (Primary) ; Cytarabine (Primary) ; Decitabine (Primary) ; Sorafenib (Primary)
  • Indications Acute biphenotypic leukaemia; Acute myeloid leukaemia; Leukaemia
  • Focus Adverse reactions

Most Recent Events

  • 03 Feb 2025 Planned initiation date changed from 31 Dec 2024 to 31 Dec 2025.
  • 03 Jul 2024 New trial record

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