Trial Profile

A Phase 1, Open-Label, First-in-Human, Dose Escalation Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of MT-303 in Adults With Advanced or Metastatic GPC3-Expressing Cancers, Including Hepatocellular Carcinoma

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 13 Jan 2026

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At a glance

18 Dec 2025 Planned number of patients changed from 48 to 70.
18 Dec 2025 Planned End Date changed from 31 May 2026 to 31 May 2028.
18 Dec 2025 Planned primary completion date changed from 31 Jul 2025 to 31 Dec 2027.

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