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A Phase 1/2 Open-Label Dose Escalation Study to Evaluate the Safety and Efficacy of AGTC-501 (rAAV2tYF-GRK1-RPGR) and a Phase 2 Randomized, Controlled, Masked, Multi-center Study Comparing Two Doses of AGTC-501 in Male Participants With X-linked Retinitis Pigmentosa

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Trial Profile

A Phase 1/2 Open-Label Dose Escalation Study to Evaluate the Safety and Efficacy of AGTC-501 (rAAV2tYF-GRK1-RPGR) and a Phase 2 Randomized, Controlled, Masked, Multi-center Study Comparing Two Doses of AGTC-501 in Male Participants With X-linked Retinitis Pigmentosa

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 29 Oct 2025

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At a glance

  • Drugs Laruparetigene zovaparvovec (Primary)
  • Indications Retinitis pigmentosa
  • Focus Adverse reactions
  • Acronyms DAWN
  • Sponsors Beacon Therapeutics

Most Recent Events

  • 04 Sep 2025 Results presented in the Beacon Therapeutics Media Release.
  • 04 Sep 2025 According to Beacon Therapeutics media release, the company presented 9+month results of this study at the EURETINA 2025 Conference being held September 4-7, 2025 in Paris, France.
  • 21 Aug 2025 According to Beacon Therapeutics media release, status changed from recruiting to active, no longer recruiting.

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