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A Phase 1/2 Open-Label Dose Escalation Study to Evaluate the Safety and Efficacy of AGTC-501 (rAAV2tYF-GRK1-RPGR) and a Phase 2 Randomized, Controlled, Masked, Multi-center Study Comparing Two Doses of AGTC-501 in Male Participants With X-linked Retinitis Pigmentosa

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Trial Profile

A Phase 1/2 Open-Label Dose Escalation Study to Evaluate the Safety and Efficacy of AGTC-501 (rAAV2tYF-GRK1-RPGR) and a Phase 2 Randomized, Controlled, Masked, Multi-center Study Comparing Two Doses of AGTC-501 in Male Participants With X-linked Retinitis Pigmentosa

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 12 May 2025

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At a glance

  • Drugs Laruparetigene zovaparvovec (Primary)
  • Indications Retinitis pigmentosa
  • Focus Adverse reactions
  • Acronyms DAWN
  • Sponsors Beacon Therapeutics

Most Recent Events

  • 06 May 2025 Results presented in the Beacon Therapeutics Media Release.
  • 06 May 2025 According to Beacon Therapeutics media release, company presented 6-month interim safety and efficacy results from at the Association for Research in Vision and Ophthalmology (ARVO) 2025 Annual Meeting being held May 4-8, 2025 in Salt Lake City.
  • 24 Apr 2025 According to Beacon Therapeutics media release, 6-month interim safety and efficacy results from this trial will be presented at the Association for Research in Vision and Ophthalmology (ARVO) 2025 Annual Meeting

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