Comparison of B-cell Depletion by Rituximab and Anti-CD 19 CAR-T Therapy in Patients With Rheumatoid Arthritis. Two-stage Interventional, Prospective, Randomized, Controlled, Open Label, Parallel-group Phase I/II Trial in Patients With Active, ACPA-positive and Treatment Refractory Rheumatoid Arthritis
Latest Information Update: 19 Nov 2025
At a glance
- Drugs KYV-101 (Primary) ; Rituximab
- Indications Rheumatoid arthritis
- Focus Adverse reactions; Therapeutic Use
- Acronyms COMPARE
Most Recent Events
- 25 Oct 2025 According to a Kyverna Therapeutics media release, data from phase I part of the trial will be featured at the American College of Rheumatology (ACR) Convergence 2025.
- 25 Oct 2025 Results published in the Media Release
- 12 Aug 2025 According to a Kyverna Therapeutics media release, data of KYV-101 in RA to be highlighted at the American College of Rheumatology (ACR) Convergence 2025 meeting in October 2025.