Trial Profile

A Randomized Phase II Study to Evaluate the Safety and Efficacy of Trastuzumab Deruxtecan Versus CDK4/6 Inhibitor-based Endocrine Therapy as First-line Therapy of HR-positive and HER2-low/Ultralow Advanced Breast Cancer Patients Classified as Non-luminal Subtype According to Gene Expression Profiling.

Status: Not yet recruiting

Phase of Trial: Phase II

Latest Information Update: 28 Apr 2025

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At a glance

Drugs Trastuzumab-deruxtecan (Primary) ; Abemaciclib; Anastrozole; Exemestane; Fulvestrant; Letrozole; Palbociclib; Ribociclib
Indications Advanced breast cancer
Focus Therapeutic Use
Acronyms PONTIAC

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