A Phase 2 Study of Defactinib and Avutometinib, in Combination With Nivolumab for Patients With Anti-PD1 Refractory LKB1-Mutant Advanced Lung Adenocarcinoma
Latest Information Update: 22 Apr 2025
At a glance
- Drugs Avutometinib (Primary) ; Defactinib (Primary) ; Nivolumab (Primary)
- Indications Adenocarcinoma; Lung cancer; Non-small cell lung cancer
- Focus Therapeutic Use
Most Recent Events
- 17 Apr 2025 Planned End Date changed from 30 Jun 2026 to 17 Sep 2028.
- 17 Apr 2025 Planned primary completion date changed from 30 Aug 2025 to 17 Mar 2028.
- 14 Aug 2024 Status changed from not yet recruiting to recruiting.