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A Phase 1/1b/2 Study of Cabozantinib in Combination With Selumetinib for Plexiform Neurofibroma in Adults and Adolescents With Neurofibromatosis Type 1

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Trial Profile

A Phase 1/1b/2 Study of Cabozantinib in Combination With Selumetinib for Plexiform Neurofibroma in Adults and Adolescents With Neurofibromatosis Type 1

Status: Not yet recruiting
Phase of Trial: Phase I/II

Latest Information Update: 21 Apr 2025

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At a glance

  • Drugs Cabozantinib (Primary) ; Selumetinib (Primary)
  • Indications Plexiform neurofibroma
  • Focus Adverse reactions

Most Recent Events

  • 16 Apr 2025 Planned End Date changed from 1 Apr 2033 to 1 Jul 2033.
  • 16 Apr 2025 Planned primary completion date changed from 1 Apr 2032 to 1 Jul 2032.
  • 16 Apr 2025 Planned initiation date changed from 1 Apr 2025 to 1 Jul 2025.

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