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A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of Taplucainium Inhalation Powder (NOC-110) in Adults with Refractory or Unexplained Chronic Cough

Trial Profile

A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of Taplucainium Inhalation Powder (NOC-110) in Adults with Refractory or Unexplained Chronic Cough

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 06 May 2025

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At a glance

  • Drugs Taplucanium (Primary)
  • Indications Cough
  • Focus Therapeutic Use
  • Acronyms ASPIRE
  • Sponsors Nocion Therapeutics

Most Recent Events

  • 28 Apr 2025 According to a Nocion Therapeutics media release, the company has appointed Dr.Matthew Frankel as a Chief Medical Officer to continue the development of this study.
  • 18 Nov 2024 According to a Nocion Therapeutics media release, the first patient has been dosed in the Phase 2b ASPIRE clinical trial of taplucainium for the treatment of chronic cough. Approximately 325 patients will be enrolled in the study at over 100 sites across the US, Canada, UK and Europe.
  • 01 Oct 2024 Status changed from not yet recruiting to recruiting.

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