Trial Profile

Phase 1 Randomized, Double-blind Dose-Escalating Study of Pfs230D1 in Combination With R21 in Matrix-M in Healthy African Adults

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 13 Feb 2026

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At a glance

Drugs Pfs25 Pfs230 malaria vaccine MVI (Primary) ; R 21 (Primary) ; Matrix M
Indications Falciparum malaria
Focus Adverse reactions
Sponsors Serum Institute of India

Most Recent Events

10 Feb 2026 Status changed from active, no longer recruiting to completed.
13 Jan 2026 Planned End Date changed from 1 Oct 2025 to 1 Feb 2026.
13 Jan 2026 Planned primary completion date changed from 1 Oct 2025 to 1 Feb 2026.

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