Trial Profile

A Prospective, Open-Label, Multicenter, Randomized Controlled Study Comparing the Efficacy and Safety of Polatuzumab Vedotin, Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone Combined With Orelabrutinib/Chidamide/Venetoclax/Lenalidomide/PD1 (Pola-RCHP-X) Versus RCHOP-X and Pola-RCHP in Previously Untreated Patients With Diffuse Large B-Cell Lymphoma

Status: Not yet recruiting

Phase of Trial: Phase II

Latest Information Update: 31 Jan 2025

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At a glance

Drugs Cyclophosphamide (Primary) ; Doxorubicin (Primary) ; Polatuzumab vedotin (Primary) ; Prednisone (Primary) ; Rituximab (Primary) ; Lenalidomide; Orelabrutinib; Penpulimab; Tucidinostat; Venetoclax; Vincristine
Indications Diffuse large B cell lymphoma
Focus Therapeutic Use

10 Dec 2024 Trial design presented at the 66th American Society of Hematology Annual Meeting and Exposition.
29 Jul 2024 New trial record

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