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A Multicenter, Randomized, Double-Blind, Placebo and Active Comparator Controlled Phase 3 Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Moderate to Severe Plaque Psoriasis (ONWARD1)

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Trial Profile

A Multicenter, Randomized, Double-Blind, Placebo and Active Comparator Controlled Phase 3 Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Moderate to Severe Plaque Psoriasis (ONWARD1)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 26 Jun 2025

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At a glance

  • Drugs ESK-001 (Primary) ; Apremilast
  • Indications Plaque psoriasis
  • Focus Registrational; Therapeutic Use
  • Acronyms ONWARD 1
  • Sponsors Alumis

Most Recent Events

  • 26 Jun 2025 Planned End Date changed from 1 Jun 2026 to 1 Dec 2026.
  • 20 Jun 2025 Planned primary completion date changed from 1 May 2026 to 1 Sep 2025.
  • 29 May 2025 Status changed from recruiting to active, no longer recruiting.

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