Efficacy and Safety of Co-administered Cagrilintide and Semaglutide (CagriSema) 1.0 mg/1.0 mg s.c. Once Weekly Versus Tirzepatide 5 mg s.c. Once Weekly in Participants With Type 2 Diabetes Inadequately Controlled on Metformin, SGLT2 Inhibitor or Both
Latest Information Update: 25 Sep 2025
At a glance
- Drugs Cagrilintide/semaglutide (Primary) ; Tirzepatide (Primary)
- Indications Type 2 diabetes mellitus
- Focus Therapeutic Use
- Acronyms REIMAGINE 5
- Sponsors Novo Nordisk
Most Recent Events
- 28 May 2025 Planned End Date changed from 18 Aug 2026 to 14 Jul 2026.
- 28 May 2025 Planned primary completion date changed from 7 Jul 2026 to 2 Jun 2026.
- 22 Apr 2025 Status changed from recruiting to active, no longer recruiting.