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A Phase 2b, Multi-centre, Randomized, Partially Placebo-controlled, Double-blind Study to Investigate the Safety and Efficacy of Sequential Therapy With Daplusiran/Tomligisiran Followed by Bepirovirsen in Participants With Chronic Hepatitis B Virus on Background Nucleos(t)Ide Analogue Therapy (B-United)

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A Phase 2b, Multi-centre, Randomized, Partially Placebo-controlled, Double-blind Study to Investigate the Safety and Efficacy of Sequential Therapy With Daplusiran/Tomligisiran Followed by Bepirovirsen in Participants With Chronic Hepatitis B Virus on Background Nucleos(t)Ide Analogue Therapy (B-United)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 11 Dec 2024

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At a glance

  • Drugs Bepirovirsen (Primary) ; JNJ 73763989 (Primary)
  • Indications Hepatitis B
  • Focus Therapeutic Use
  • Acronyms B-UNITED
  • Sponsors GSK

    • Most Recent Events

    • 09 Dec 2024 Planned End Date changed from 4 Jan 2028 to 29 Oct 2027.
    • 09 Dec 2024 Planned primary completion date changed from 4 Jan 2028 to 29 Oct 2027.
    • 09 Dec 2024 Status changed from not yet recruiting to recruiting.

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