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A Phase 1, Randomized, Double-blind, Placebo-controlled, Drug-drug Interaction, Pharmacokinetic, and Safety Study of Cefiderocol in Combination With Xeruborbactam in Healthy Adult Participants

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Trial Profile

A Phase 1, Randomized, Double-blind, Placebo-controlled, Drug-drug Interaction, Pharmacokinetic, and Safety Study of Cefiderocol in Combination With Xeruborbactam in Healthy Adult Participants

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 11 Dec 2025

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At a glance

  • Drugs Cefiderocol (Primary) ; Xeruborbactam (Primary)
  • Indications Bacterial infections
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Qpex Biopharma

Most Recent Events

  • 28 Nov 2025 Status changed from active, no longer recruiting to completed.
  • 03 Nov 2025 Status changed from recruiting to active, no longer recruiting.
  • 11 Aug 2025 Number of treatment arm has been changed from 2 to 6, patient number also increased and primary endpoint has been amended.

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