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A Single-Arm, Open-Label, Safety Study in Patients With Generalized Lipodystrophy Switching From Metreleptin to Mibavademab, A Leptin Receptor Agonist Antibody

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Trial Profile

A Single-Arm, Open-Label, Safety Study in Patients With Generalized Lipodystrophy Switching From Metreleptin to Mibavademab, A Leptin Receptor Agonist Antibody

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 14 Aug 2025

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At a glance

  • Drugs Mibavademab (Primary)
  • Indications Congenital generalised lipodystrophy
  • Focus Adverse reactions
  • Sponsors Regeneron Pharmaceuticals

Most Recent Events

  • 31 Jul 2025 Planned End Date changed from 28 Jun 2027 to 3 Nov 2026.
  • 31 Jul 2025 Planned primary completion date changed from 8 Mar 2027 to 14 Jul 2026.
  • 31 Jul 2025 Status changed from recruiting to active, no longer recruiting.

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