Trial Profile

FIRST-IN-HUMAN (FIH), OPEN-LABEL, PHASE 1 DOSE ESCALATION AND EXPANSION STUDY DESIGNED TO EVALUATE THE SAFETY, TOLERABILITY, PK, PD, AND PRELIMINARY CLINICAL ACTIVITY OF PF-07826390 AS A SINGLE AGENT OR IN COMBINATION TREATMENT FOR PARTICIPANTS WITH ADVANCED SOLID TUMORS

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 09 Apr 2025

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At a glance

Drugs PF 07826390 (Primary) ; Sasanlimab
Indications Colorectal cancer; Non-small cell lung cancer; Renal cell carcinoma; Solid tumours
Focus Adverse reactions; First in man; Therapeutic Use
Sponsors Pfizer

06 Apr 2025 Planned End Date changed from 14 Feb 2030 to 21 Oct 2025.
06 Apr 2025 Planned primary completion date changed from 14 Feb 2029 to 21 Oct 2025.
06 Apr 2025 Status changed from recruiting to active, no longer recruiting.

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