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A Phase 1/2A Dose-Escalating Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ARO-ALK7 in Adult Volunteers With Obesity With and Without Type 2 Diabetes Mellitus

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A Phase 1/2A Dose-Escalating Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ARO-ALK7 in Adult Volunteers With Obesity With and Without Type 2 Diabetes Mellitus

Status: Not yet recruiting
Phase of Trial: Phase I/II

Latest Information Update: 29 Apr 2025

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At a glance

  • Drugs ARO ALK7 (Primary) ; Tirzepatide
  • Indications Metabolic disorders; Obesity; Type 2 diabetes mellitus
  • Focus Adverse reactions; First in man
  • Acronyms AROALK7-1001
  • Sponsors Arrowhead Pharmaceuticals

Most Recent Events

  • 24 Apr 2025 Status changed from planning to not yet recruiting.
  • 06 Mar 2025 According to an Arrowhead Pharmaceuticals media release, company anticipates initial data from the single-ascending dose portion of the study possible by year end 2025.
  • 25 Feb 2025 According to an Arrowhead Pharmaceuticals media release, company anticipates will begin dosing in the second quarter of 2025.

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