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A Phase 1 Randomized, Placebo- and Active-controlled, Observer-blind Study in Older Adults With Run-in in Young Adults to Evaluate the Safety, Reactogenicity, and Immunogenicity of Four Dose Levels of VXB-241, A Molecular Clamp Stabilized Prefusion F Glycoprotein Subunit Bivalent Vaccine Candidate for the Prevention of Lower Respiratory Tract Disease Caused by Respiratory Syncytial Virus (RSV) And Human Metapneumovirus (HMPV)

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Trial Profile

A Phase 1 Randomized, Placebo- and Active-controlled, Observer-blind Study in Older Adults With Run-in in Young Adults to Evaluate the Safety, Reactogenicity, and Immunogenicity of Four Dose Levels of VXB-241, A Molecular Clamp Stabilized Prefusion F Glycoprotein Subunit Bivalent Vaccine Candidate for the Prevention of Lower Respiratory Tract Disease Caused by Respiratory Syncytial Virus (RSV) And Human Metapneumovirus (HMPV)

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 11 Jun 2025

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At a glance

Most Recent Events

  • 31 Jan 2025 Status changed from recruiting to active, no longer recruiting.
  • 21 Nov 2024 According to Vicebio Media Realease, company is progressing into the second stage of its clinical study of VXB-241 and is now enrolling individuals aged 60 years of age and above.
  • 23 Sep 2024 According to Vicebio Media Realease, the company has Commenced this Phase I clinical study of bivalent vaccine targeting both Respiratory Syncytial Virus (RSV) and Human Metapneumovirus (hMPV). Initial clinical readouts of the Phase 1 study are expected mid 2025.

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