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A Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Clinical Activity of GSK5764227 as Monotherapy and in Combination in Participants With Advanced Solid Tumors

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Trial Profile

A Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Clinical Activity of GSK5764227 as Monotherapy and in Combination in Participants With Advanced Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 04 Jun 2025

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At a glance

  • Drugs HS-20093 (Primary) ; Atezolizumab; Bevacizumab; Carboplatin; Cetuximab; Cisplatin; Durvalumab; Fluorouracil; Folinic acid; Pembrolizumab; Topotecan
  • Indications Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors GSK

Most Recent Events

  • 30 Apr 2025 Trial design presented at the 116th Annual Meeting of the American Association for Cancer Research
  • 18 Mar 2025 Fluorouracil and folinic acid removed from the interventions
  • 18 Mar 2025 Planned number of patients changed from 240 to 281.

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