Phase 1/2 Clinical Trial of S227928, an Anti-CD74 Antibody-Drug Conjugate Targeting MCL-1, as a Single Agent and in Combination With Venetoclax in Patients With Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS)/AML, or Chronic Myelomonocytic Leukemia (CMML)

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 06 Mar 2025

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At a glance

Drugs S 227928 (Primary) ; Venetoclax
Indications Acute myeloid leukaemia; Chronic myelomonocytic leukaemia; Myelodysplastic syndromes
Focus Adverse reactions; Therapeutic Use
Sponsors Servier

Most Recent Events

27 Feb 2025 Status changed from not yet recruiting to recruiting.
23 Aug 2024 New trial record

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