A Phase 3 Multicenter Open-label Study of Taletrectinib Versus a Standard of Care ROS1-Tyrosine Kinase Inhibitor (Crizotinib) in TKI-Naïve Patients With ROS1-Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer (TRUST-III)
Latest Information Update: 30 Apr 2026
At a glance
- Drugs Taletrectinib (Primary) ; Crizotinib
- Indications Non-small cell lung cancer
- Focus Registrational; Therapeutic Use
- Acronyms TRUST-III
- Sponsors Nuvation Bio
Most Recent Events
- 13 Apr 2026 Planned number of patients changed from 138 to 194.
- 25 Mar 2025 According to Nuvation Bio media release, data from this study will be reported in a mini oral presentation at the European Lung Cancer Congress taking place March 26-29, 2025 in Paris, France.
- 11 Mar 2025 Status changed from not yet recruiting to recruiting.