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An Open-label, Non-randomised, Fixed-sequence, Two Period, Phase I Trial to Evaluate the Effect of Different Doses of BI 456906 (Survodutide) on the Single Dose Pharmacokinetics of Bupropion, Caffeine and Midazolam on Otherwise Healthy Volunteers With Overweight or Obesity

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An Open-label, Non-randomised, Fixed-sequence, Two Period, Phase I Trial to Evaluate the Effect of Different Doses of BI 456906 (Survodutide) on the Single Dose Pharmacokinetics of Bupropion, Caffeine and Midazolam on Otherwise Healthy Volunteers With Overweight or Obesity

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 17 Dec 2024

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At a glance

  • Drugs Survodutide (Primary) ; Bupropion; Caffeine; Midazolam
  • Indications Liver cirrhosis; Non-alcoholic steatohepatitis; Obesity; Type 2 diabetes mellitus
  • Focus Pharmacokinetics
  • Sponsors Boehringer Ingelheim

    • Most Recent Events

    • 13 Dec 2024 Status changed from recruiting to active, no longer recruiting.
    • 17 Sep 2024 Status changed from not yet recruiting to recruiting.
    • 26 Aug 2024 New trial record

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