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Phase I Trial for Patients With Advanced Hematologic Malignancies Undergoing Allogeneic Hematopoietic Cell Transplantation From an HLA-Mismatched Donor (7/8) With Orca-T

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Trial Profile

Phase I Trial for Patients With Advanced Hematologic Malignancies Undergoing Allogeneic Hematopoietic Cell Transplantation From an HLA-Mismatched Donor (7/8) With Orca-T

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 31 Jul 2025

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At a glance

  • Drugs Orca-T (Primary) ; Ruxolitinib; Tacrolimus
  • Indications Acute biphenotypic leukaemia; Acute myeloid leukaemia; Myelodysplastic syndromes
  • Focus Adverse reactions

Most Recent Events

  • 16 Jul 2025 Planned initiation date changed from 1 Jun 2025 to 1 Sep 2025.
  • 19 Mar 2025 Planned initiation date changed from 1 Jan 2025 to 1 Jun 2025.
  • 03 Dec 2024 Planned initiation date changed from 1 Oct 2024 to 1 Jan 2025.

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