RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-MASKED STUDY OF THE SAFETY AND EFFICACY OF POS (0.75% PHENTOLAMINE OPHTHALMIC SOLUTION) IN PARTICIPANTS WITH PREVIOUS KERATOREFRACTIVE SURGERY WITH DECREASED VISUAL ACUITY UNDER MESOPIC CONDITIONS
Latest Information Update: 08 Oct 2025
At a glance
- Drugs Phentolamine (Primary)
- Indications Nyctalopia
- Focus Registrational; Therapeutic Use
- Acronyms LYNX-3
- Sponsors Ocuphire Pharma
Most Recent Events
- 04 Sep 2025 According to an Opus Genetics media release, LYNX-3 is the second of two, pivotal Phase 3 studies and follows the same study design and patient population as the first study, LYNX-2- for chronic night driving impairment in keratorefractive patients with reduced mesopic vision. These studies have Fast Track designation from the USFDA and are being conducted under a Special Protocol Assessment (SPA).
- 04 Sep 2025 According to an Opus Genetics media release, 1st patient has been dosed in this trial.
- 02 Jun 2025 According to an Viatris Pharma media release, this LYNX-3 is anticipated to start shortly with results expected in the first half of 2026