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A Phase IIb Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety and Tolerability of AZD5004 in Participants Living With Obesity or Overweight With Comorbidity

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Trial Profile

A Phase IIb Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety and Tolerability of AZD5004 in Participants Living With Obesity or Overweight With Comorbidity

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 02 Mar 2026

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At a glance

  • Drugs Elecoglipron (Primary)
  • Indications Obesity
  • Focus Therapeutic Use
  • Acronyms VISTA
  • Sponsors AstraZeneca

Most Recent Events

  • 10 Feb 2026 According to AstraZeneca media release, primary endpoint (Proportion of participants with weight loss 5% from baseline weight) has been met.
  • 10 Feb 2026 According to AstraZeneca media release, primary endpoint (Percent change in body weight from baseline) has been met.
  • 18 Dec 2025 Status changed from active, no longer recruiting to completed.

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