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A Phase 1/2a, Open-Label Study of Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SA53-OS, an MDM2 Inhibitor, in Patients With Locally Advanced or Metastatic p53 Wild-Type Solid Tumors

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Trial Profile

A Phase 1/2a, Open-Label Study of Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SA53-OS, an MDM2 Inhibitor, in Patients With Locally Advanced or Metastatic p53 Wild-Type Solid Tumors

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 07 Jun 2025

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At a glance

  • Drugs SA53 MDM2 (Primary)
  • Indications Non-Hodgkin's lymphoma
  • Focus Adverse reactions
  • Sponsors Lamassu Pharma

Most Recent Events

  • 13 Mar 2025 Planned primary completion date changed from 1 Feb 2026 to 1 Mar 2026.
  • 13 Mar 2025 Status changed from not yet recruiting to recruiting.
  • 29 Jan 2025 Planned End Date changed from 1 Jun 2028 to 1 Dec 2028.

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